Analysis of Factors Influencing Pregnancy Rate in Frozen- thawed Embryo Transfer

نویسندگان

  • Lu LI
  • Xiao-xi SUN
  • Jun-ling CHEN
  • Xiao-hong GAO
  • Yong-wei WANG
  • Jie-wei TAO
  • Li-nan CHENG
چکیده

Objective To analyse factors influencing the outcome of frozen-thawed embryo transfer (FET) Method A retrospective analysis was performed in our center on 129 thawing cycles from March 2001 to April 2003. The related parameters were compared between conceived and non-conceived cycles. Results There were totally 129 clinical pregnancies in these transfers (pregnancy rate: 27.1%). Frozen-thawed embryos were transferred to natural cycles and CC cycling and hormone replacement treatment had equal success. Groups of IVF and ICSI did not differ significantly in pregnancy rates (P>0.05). The pregnancy rates for one, two, three and four pre-embryos transfer were 0, 20.0%,44.1% and 75.0%, respectively (P<0.05). There were statistical differences between pregnancy group or nonpregnancy group in the endometrial thickness, CES, CES/No. of embryo. A higher pregnancy rate was observed in embryo transfers which had at least one 4-cell grade I embryo (d 2)(P<0.01). Conclusions The most important factors influencing the implantation rate and pregnancy rate of frozen-thawed embryo transfer are age, endometrium thickness,and the number, morphology and growth rate of transferred frozen embryos of women participants.

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تاریخ انتشار 2005